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Update on the OMERACT Magnetic Resonance Imaging Task Force: Research and Future Directions

Identifieur interne : 003F05 ( Main/Exploration ); précédent : 003F04; suivant : 003F06

Update on the OMERACT Magnetic Resonance Imaging Task Force: Research and Future Directions

Auteurs : Philip G. Conaghan [Royaume-Uni, Nouvelle-Zélande, Australie, États-Unis, Norvège, France, Israël, Danemark, Allemagne] ; Fiona M. Mcqueen ; Paul Bird ; Charles Peterfy ; Espen Haavardsholm ; Frédérique Gandjbakhch ; Iris Eshed ; Ida K. Haugen ; Siri Lillegraven ; Uffe M Ller D Hn ; Bo Ejbjerg ; Violaine Foltz ; Laura Coates ; Pernille B Yesen ; Kay-Geert Hermann ; Jane Freeston ; Marissa Lassere ; Philip O'Connor ; Paul Emery ; Harry Genant ; Mikkel Stergaard

Source :

RBID : Pascal:14-0078232

Descripteurs français

English descriptors

Abstract

Magnetic resonance imaging (MRI) provides an important biomarker across a range of rheumatological diseases. At the Outcome Measures in Rheumatology (OMERACT) 11 meeting, the MRI task force continued its work of developing and improving the use of MRI outcomes for use in clinical trials. The breadth of pathology in the Rheumatoid Arthritis MRI Score has been strengthened with further work on the development of a joint space narrowing score, and a series of exercises presented at OMERACT 11 demonstrated good reliability and construct validity for this assessment. Understanding the importance of residual inflammation after RA treatment remains a major focus of the group's work. Analyses were presented on defining the level of synovitis (using MRI scores of a single hand) that would predict absence of erosion progression. The development of the OMERACT Hand Osteoarthritis MRI score has continued with substantial work presented on its iterative development, including pathology definition, scaling, and subsequent reliability of the score. Optimizing the role of MRI as a robust biomarker and surrogate outcome remains a priority for this group.


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Le document en format XML

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<term>Arthritis, Rheumatoid (pathology)</term>
<term>Disease Progression</term>
<term>Hand</term>
<term>Humans</term>
<term>Joint space</term>
<term>Magnetic Resonance Imaging (methods)</term>
<term>Nuclear magnetic resonance imaging</term>
<term>Osteoarthritis</term>
<term>Osteoarthritis (pathology)</term>
<term>Outcome Assessment (Health Care)</term>
<term>Reproducibility of Results</term>
<term>Rheumatology</term>
<term>Severity of Illness Index</term>
<term>Synovitis (pathology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Arthrose (anatomopathologie)</term>
<term>Humains</term>
<term>Imagerie par résonance magnétique ()</term>
<term>Indice de gravité médicale</term>
<term>Polyarthrite rhumatoïde (anatomopathologie)</term>
<term>Reproductibilité des résultats</term>
<term>Rhumatologie</term>
<term>Synovite (anatomopathologie)</term>
<term>Évaluation de résultat (soins)</term>
<term>Évolution de la maladie</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr">
<term>Arthrose</term>
<term>Polyarthrite rhumatoïde</term>
<term>Synovite</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en">
<term>Magnetic Resonance Imaging</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en">
<term>Arthritis, Rheumatoid</term>
<term>Osteoarthritis</term>
<term>Synovitis</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Disease Progression</term>
<term>Humans</term>
<term>Outcome Assessment (Health Care)</term>
<term>Reproducibility of Results</term>
<term>Rheumatology</term>
<term>Severity of Illness Index</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr">
<term>Humains</term>
<term>Imagerie RMN</term>
<term>Imagerie par résonance magnétique</term>
<term>Indice de gravité médicale</term>
<term>Main</term>
<term>Arthrose</term>
<term>Reproductibilité des résultats</term>
<term>Rhumatologie</term>
<term>Interligne articulaire</term>
<term>Évaluation de résultat (soins)</term>
<term>Évolution de la maladie</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">Magnetic resonance imaging (MRI) provides an important biomarker across a range of rheumatological diseases. At the Outcome Measures in Rheumatology (OMERACT) 11 meeting, the MRI task force continued its work of developing and improving the use of MRI outcomes for use in clinical trials. The breadth of pathology in the Rheumatoid Arthritis MRI Score has been strengthened with further work on the development of a joint space narrowing score, and a series of exercises presented at OMERACT 11 demonstrated good reliability and construct validity for this assessment. Understanding the importance of residual inflammation after RA treatment remains a major focus of the group's work. Analyses were presented on defining the level of synovitis (using MRI scores of a single hand) that would predict absence of erosion progression. The development of the OMERACT Hand Osteoarthritis MRI score has continued with substantial work presented on its iterative development, including pathology definition, scaling, and subsequent reliability of the score. Optimizing the role of MRI as a robust biomarker and surrogate outcome remains a priority for this group.</div>
</front>
</TEI>
<affiliations>
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<li>Allemagne</li>
<li>Australie</li>
<li>Danemark</li>
<li>France</li>
<li>Israël</li>
<li>Norvège</li>
<li>Nouvelle-Zélande</li>
<li>Royaume-Uni</li>
<li>États-Unis</li>
</country>
<region>
<li>Angleterre</li>
<li>Berlin</li>
<li>Californie</li>
<li>Hovedstaden</li>
<li>Nouvelle-Galles du Sud</li>
<li>Yorkshire-et-Humber</li>
<li>Île-de-France</li>
<li>Østlandet</li>
</region>
<settlement>
<li>Berlin</li>
<li>Copenhague</li>
<li>Leeds</li>
<li>Oslo</li>
<li>Paris</li>
<li>Sydney</li>
</settlement>
<orgName>
<li>Université de Leeds</li>
</orgName>
</list>
<tree>
<noCountry>
<name sortKey=" Stergaard, Mikkel" sort=" Stergaard, Mikkel" uniqKey=" Stergaard M" first="Mikkel" last=" Stergaard">Mikkel Stergaard</name>
<name sortKey="B Yesen, Pernille" sort="B Yesen, Pernille" uniqKey="B Yesen P" first="Pernille" last="B Yesen">Pernille B Yesen</name>
<name sortKey="Bird, Paul" sort="Bird, Paul" uniqKey="Bird P" first="Paul" last="Bird">Paul Bird</name>
<name sortKey="Coates, Laura" sort="Coates, Laura" uniqKey="Coates L" first="Laura" last="Coates">Laura Coates</name>
<name sortKey="D Hn, Uffe M Ller" sort="D Hn, Uffe M Ller" uniqKey="D Hn U" first="Uffe M Ller" last="D Hn">Uffe M Ller D Hn</name>
<name sortKey="Ejbjerg, Bo" sort="Ejbjerg, Bo" uniqKey="Ejbjerg B" first="Bo" last="Ejbjerg">Bo Ejbjerg</name>
<name sortKey="Emery, Paul" sort="Emery, Paul" uniqKey="Emery P" first="Paul" last="Emery">Paul Emery</name>
<name sortKey="Eshed, Iris" sort="Eshed, Iris" uniqKey="Eshed I" first="Iris" last="Eshed">Iris Eshed</name>
<name sortKey="Foltz, Violaine" sort="Foltz, Violaine" uniqKey="Foltz V" first="Violaine" last="Foltz">Violaine Foltz</name>
<name sortKey="Freeston, Jane" sort="Freeston, Jane" uniqKey="Freeston J" first="Jane" last="Freeston">Jane Freeston</name>
<name sortKey="Gandjbakhch, Frederique" sort="Gandjbakhch, Frederique" uniqKey="Gandjbakhch F" first="Frédérique" last="Gandjbakhch">Frédérique Gandjbakhch</name>
<name sortKey="Genant, Harry" sort="Genant, Harry" uniqKey="Genant H" first="Harry" last="Genant">Harry Genant</name>
<name sortKey="Haavardsholm, Espen" sort="Haavardsholm, Espen" uniqKey="Haavardsholm E" first="Espen" last="Haavardsholm">Espen Haavardsholm</name>
<name sortKey="Haugen, Ida K" sort="Haugen, Ida K" uniqKey="Haugen I" first="Ida K." last="Haugen">Ida K. Haugen</name>
<name sortKey="Hermann, Kay Geert" sort="Hermann, Kay Geert" uniqKey="Hermann K" first="Kay-Geert" last="Hermann">Kay-Geert Hermann</name>
<name sortKey="Lassere, Marissa" sort="Lassere, Marissa" uniqKey="Lassere M" first="Marissa" last="Lassere">Marissa Lassere</name>
<name sortKey="Lillegraven, Siri" sort="Lillegraven, Siri" uniqKey="Lillegraven S" first="Siri" last="Lillegraven">Siri Lillegraven</name>
<name sortKey="Mcqueen, Fiona M" sort="Mcqueen, Fiona M" uniqKey="Mcqueen F" first="Fiona M." last="Mcqueen">Fiona M. Mcqueen</name>
<name sortKey="O Connor, Philip" sort="O Connor, Philip" uniqKey="O Connor P" first="Philip" last="O'Connor">Philip O'Connor</name>
<name sortKey="Peterfy, Charles" sort="Peterfy, Charles" uniqKey="Peterfy C" first="Charles" last="Peterfy">Charles Peterfy</name>
</noCountry>
<country name="Royaume-Uni">
<region name="Angleterre">
<name sortKey="Conaghan, Philip G" sort="Conaghan, Philip G" uniqKey="Conaghan P" first="Philip G." last="Conaghan">Philip G. Conaghan</name>
</region>
<name sortKey="Conaghan, Philip G" sort="Conaghan, Philip G" uniqKey="Conaghan P" first="Philip G." last="Conaghan">Philip G. Conaghan</name>
</country>
<country name="Nouvelle-Zélande">
<noRegion>
<name sortKey="Conaghan, Philip G" sort="Conaghan, Philip G" uniqKey="Conaghan P" first="Philip G." last="Conaghan">Philip G. Conaghan</name>
</noRegion>
</country>
<country name="Australie">
<region name="Nouvelle-Galles du Sud">
<name sortKey="Conaghan, Philip G" sort="Conaghan, Philip G" uniqKey="Conaghan P" first="Philip G." last="Conaghan">Philip G. Conaghan</name>
</region>
<name sortKey="Conaghan, Philip G" sort="Conaghan, Philip G" uniqKey="Conaghan P" first="Philip G." last="Conaghan">Philip G. Conaghan</name>
</country>
<country name="États-Unis">
<region name="Californie">
<name sortKey="Conaghan, Philip G" sort="Conaghan, Philip G" uniqKey="Conaghan P" first="Philip G." last="Conaghan">Philip G. Conaghan</name>
</region>
<name sortKey="Conaghan, Philip G" sort="Conaghan, Philip G" uniqKey="Conaghan P" first="Philip G." last="Conaghan">Philip G. Conaghan</name>
</country>
<country name="Norvège">
<region name="Østlandet">
<name sortKey="Conaghan, Philip G" sort="Conaghan, Philip G" uniqKey="Conaghan P" first="Philip G." last="Conaghan">Philip G. Conaghan</name>
</region>
</country>
<country name="France">
<region name="Île-de-France">
<name sortKey="Conaghan, Philip G" sort="Conaghan, Philip G" uniqKey="Conaghan P" first="Philip G." last="Conaghan">Philip G. Conaghan</name>
</region>
</country>
<country name="Israël">
<noRegion>
<name sortKey="Conaghan, Philip G" sort="Conaghan, Philip G" uniqKey="Conaghan P" first="Philip G." last="Conaghan">Philip G. Conaghan</name>
</noRegion>
</country>
<country name="Danemark">
<region name="Hovedstaden">
<name sortKey="Conaghan, Philip G" sort="Conaghan, Philip G" uniqKey="Conaghan P" first="Philip G." last="Conaghan">Philip G. Conaghan</name>
</region>
<name sortKey="Conaghan, Philip G" sort="Conaghan, Philip G" uniqKey="Conaghan P" first="Philip G." last="Conaghan">Philip G. Conaghan</name>
<name sortKey="Conaghan, Philip G" sort="Conaghan, Philip G" uniqKey="Conaghan P" first="Philip G." last="Conaghan">Philip G. Conaghan</name>
</country>
<country name="Allemagne">
<region name="Berlin">
<name sortKey="Conaghan, Philip G" sort="Conaghan, Philip G" uniqKey="Conaghan P" first="Philip G." last="Conaghan">Philip G. Conaghan</name>
</region>
</country>
</tree>
</affiliations>
</record>

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